Natural Polyphenol Engineering Field Crops based Diet to Promote Innate Immunity to Combat Covid-19 Disease.

Abstract

Due to Covid-19, quarter a million patients have already died worldwide, and evidence showed a clear association between this death and multiple organ dysfunction cytokine storms. No sustainable remedy against this disease has been found and many solutions are being considered to dig out this virus by inventing humoral and cellular immunity capacity building methods as well as food-based remedies. COVID-19 has added an extra burden to the low-income country's health care system while they are still struggling with many challenges including malnutrition, sanitary, safe drinking water. Natural polyphenol engineering field crops (NPEF) based diet could help them to harness innate immunity to prevent or attenuate the SARS-Cov-2 infection as well as reducing the secondary/co-infection by bacteria and fungus of the hospitalized patients. Polyphenols are immunomodulators and have antibacterial, antiviral, anti-cancer, anti-diabetic, anti-inflammatory, coronary heart disease prevention effects together with the ability to transport other active molecules. Interaction of polyphenols increases the efficacy of vitamin D. This review explored the potentials of polyphenols and their available sources to address the chronic diseases including Covid-19 and proposed a food prescription for Bangladesh to improve their innate immunity system.

This article is a preprint and has not been peer reviewed

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